KCNQ ion channel protein structure

KCNQ ion channel protein structure

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Caption: KCNQ ion channel protein structure. Molecular model showing the protein structure of an ion channel domain. Ion channels are membrane-spanning proteins that form a pathway for the movement of inorganic ions across cell membranes. This is the coiled tetramerization domain from Kv7.4 channels. The family of Kv7.x (KCNQ) voltage-gated potassium channels form cardiac, auditory and neuronal currents. There are five subtypes, of which this is the fourth (KQT member 4). Kv7 subfamily mutations play a role in human conditions such as arrhythmias, deafness, and epilepsy.

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