Credit: FRANCIS LEROY & MATHILDE VANSPEYBROUCK, BIOCOSMOS/SCIENCE PHOTO LIBRARY

Caption: Animation showing the effects of a transition mutation in a DNA strand. In the DNA strand at left, one adenine (A) base randomly mutates into hypoxanthine (tautomerous with 6-hydroxypurine, H). This can bind to adenine, thymine (T) or cytosine (C). When the DNA replicates, this can cause the wrong base (C) to form on the new strand, which then pairs with a guanine (G) when the DNA forms a double strand again. When this mutated DNA is translated into a protein, the new base sequence will produce a mutated version of the protein it codes for, potentially causing illness or death.

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Keywords: adenine, biochemical, biochemistry, biological, biology, chemical, chemistry, copy, copying, cytosine, disease, disorder, dna, education, educational, error, gene, genes, genetics, guanine, hydroxypurine, hypoxanthine, label, labeled, labelled, labels, molecule, mutant, mutated, point mutation, replicating, replication, sequence, single base substitution, strand, thymine

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Transition mutation in DNA

K003/7583 Rights Managed

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Duration: 00:01:12.15

Frame size: 1280x720

Frame rate: 25

Audio: No

Format: QuickTime, Photo JPEG 100%, progressive scan, square pixels

File size: 307.3M

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Capture format: QuickTime Animation

Codec: H.264

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