Cre-Lox recombination, molecular model

Cre-Lox recombination, molecular model

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Credit: LAGUNA DESIGN/SCIENCE PHOTO LIBRARY

Caption: Cre-Lox recombination. Molecular model of the enzyme CRE (cyclization recombination) recombinase (beige) mediating the recombination of strands of DNA (deoxyribonucleic acid, red and blue). It is doing this at a specific target sequence, called the Lox sequence, found in the bacteriophage P1. Cre-Lox recombination is used in genetically modified organisms to allow researchers to control gene expression and delete or insert DNA sequences.

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