Credit: FRANCIS LEROY & MATHILDE VANSPEYBROUCK, BIOCOSMOS/SCIENCE PHOTO LIBRARY

Caption: Nonsense mutation, animation. This is a genetic mutation in a DNA (deoxyribonucleic acid) sequence that results in the production of an incomplete protein. Prior to protein formation DNA (red) is transcribed into messenger RNA (ribonucleic acid, green). DNA and RNA are made up of a chain of many small molecules, known as nucleotides. During protein formation these nucleotides are read in groups of three called codons. Each codon corresponds to a specific amino acid (blue), which is used by the cell to build a complete protein. This normal process is shown in the upper frame. In the lower frame a mutation has changed the codon for an amino acid (UUG) into a stop codon (UAG), which brings the protein formation to an end. The resulting protein will be shorter than normal and is unlikely to function.

Release details: Model release not required. Property release not required.

Keywords: adenine, amino acid, animated, animation, base, base pairing, base pairs, bases, biological, biology, black background, chemical bases, codon, cytosine, deoxyribonucleic acid, dna, gene, genetics, guanine, labeled, labelled, labels, messenger rna, mrna, mutate, mutation, non-sense, non-sense mutation, nonsense, nonsense mutation, nucleic acid, nucleobase, nucleotide, polypeptide, polypeptide chain, protein, ribonucleic acid, rna, stop codon, text, thymine, transcription, translation

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Nonsense mutation, animation

K003/7591 Rights Managed

Downloadable master

Duration: 00:01:00

Frame size: 1280x720

Frame rate: 50

Audio: No

Format: QuickTime, Photo JPEG 100%, progressive scan, square pixels

File size: 603.8M

Original

Capture format: QuickTime Animation

Codec: H.264

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