Credit: FRANCIS LEROY & MATHILDE VANSPEYBROUCK, BIOCOSMOS/SCIENCE PHOTO LIBRARY

Caption: Frameshift mutation, animation. This is a change in a DNA (deoxyribonucleic acid) sequence caused by the addition or deletion of a single nucleotide. Prior to protein formation DNA (red) is transcribed into messenger RNA (ribonucleic acid, green). DNA and RNA are made up of a chain of many small molecules, known as nucleotides. During protein formation these nucleotides are read in groups of three called codons. Each codon corresponds to a specific amino acid (blue), which is used by the cell to build a complete protein. The normal process is shown in the top frame. In the lower frame a thymine nucleotide (T) is added. The code is now read differently, resulting in a considerable change in protein structure.

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Keywords: adenine, amino acid, amino acids, base, base pairing, base pairs, bases, biology, chemical bases, codon, cytosine, deoxyribonucleic acid, dna, frame-shift mutation, frameshift mutation, gene, genetic, genetics, guanine, isoleucine, messenger rna, mrna, mutate, mutation, nucleic acid, nucleobase, nucleotide, nucleotides, polypeptide, polypeptide chain, protein, ribonucleic acid, rna, thymine, transcription, translation

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Frameshift mutation, animation

K003/7596 Rights Managed

Downloadable master

Duration: 00:01:00

Frame size: 1280x720

Frame rate: 50

Audio: No

Format: QuickTime, Photo JPEG 100%, progressive scan, square pixels

File size: 485.2M

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Capture format: QuickTime Animation

Codec: H.264

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