Blood coagulation cascade, artwork

Blood coagulation cascade, artwork

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Credit: JOSE ANTONIO PENAS/SCIENCE PHOTO LIBRARY

Caption: Blood coagulation cascade. Artwork of the biochemical cascade of blood chemicals and proteins during blood clotting (coagulation). The blood vessel and its layered wall is at upper left. The main diagram shows a clot forming at the damaged area (upper right). This occurs via reaction chains known as pathways mediated by factor X proteins (red spheres). The extrinsic pathway (down centre, blue arrows) and intrinsic pathway (down left, yellow arrows) unite in the common pathway (up right, from thrombin, yellow sphere) to form the blood clot. This consists of fibrin (yellow trefoils), platelets (pink puzzle pieces), red blood cells (red discs), and white blood cells (light blue spheres).

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