Light micrograph (LM) showing invasive squamous carcinoma. In a well-differentiated squamous carcinoma, as shown in this example from the pinna, there may be hyperkeratosis, parakeratotis, or crusting ulceration over an area of proliferating keratinocytes. Cytologically, the cells exhibit features of atypica with plenomorphism, nuclear hyperchromatism, and increase in mitoses. The main feature of this lesion is invasion of the dermis by the proliferating cells. Magnification unknown.
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