Normal and Sickle Red Blood Cells, SEM

Normal and Sickle Red Blood Cells, SEM

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Credit: Mary Martin/SCIENCE PHOTO LIBRARY

Caption: Colour enhanced composite of scanning electron micrographs of one normal erythrocyte or red blood cell (left) and one showing typical characteristics of sickle cell anaemia (right). Sickle cell anaemia is a hereditary disease of the blood in which abnormal, crescent-shaped erythrocytes are present, due to the existence of abnormal haemoglobin in the red blood cells. Sickled cells interfere with oxygen transport, obstruct capillary blood flow, and cause fever and severe pain in joints and the abdomen. A high incidence of the gene coding for sickle cell exists among Mediterranean and African populations and in African American populations in the United States.

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Keywords: abnormal, abnormal blood cell, abnormal haemoglobin, anaemia, anaemic, blood, blood cell, blood disease, blood disorder, cell, colorized, comparison, composite, disease, drepanocytosis, enhanced, erythrocyte, haemoglobin, histological, histology, medical, micrograph, micrography, microscopy, normal, pathology, red blood cell, scanning electron micrograph, scanning electron microscopy, sem, sickle anaemia, sickle cell, sickle cell anaemia, sickle cell disease, sickle cell haemoglobin, sickle-cell anaemia, sickle-cell disease, sickle-cell haemoglobin

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