Elastase molecule

Elastase molecule

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Credit: ALFRED PASIEKA/SCIENCE PHOTO LIBRARY

Caption: Elastase molecule. Computer model of elastase, an enzyme produced in the pancreas that catalyses the hydrolysis of elastin. It is a compact globular protein consisting of a single polypeptide chain of 240 amino acids, which are cross-linked by 4 disulphide bridges. In connection with pancreativ functions Pancreatic Elastase (PE) is a simple, noninvasive fecal marker for assessing exocrine pancreatic function, allowing the clinician to establish a prompt and reliable diagnosis with high degrees of sensitivity (90%-100%) and specificity (93%-98%) in suspected cases of pancreatic insufficiency.

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Keywords: elastase, enzyme, enzymes, exocrine, fecal, function, globular protein, hydrolysing, hydrolysis, insufficiency, marker, model, modelling, molecular, molecule, molecules, pancreas, pancreatic, pe, polypeptide, prancreas elastase, protease, protein, proteolytic, proteomics, secretion

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