Sir3 gene silencer acting on DNA

Sir3 gene silencer acting on DNA

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Credit: LAGUNA DESIGN/SCIENCE PHOTO LIBRARY

Caption: Sir3 gene silencer acting on DNA, molecular model. Sir3 (light blue) is acting on a circular strand of DNA (deoxyribonucleic acid, pink). Sir3 is an example of a silent information regulator (Sir) found in yeast such as Saccharomyces cerevisiae. Here, the DNA is wrapped around a histone core (orange-green), forming a structure called a nucleosome. The region of the Sir3 gene silencer shown here is the BAH (bromo-associated homology) domain.

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