Pseudoxanthoma elasticum

Pseudoxanthoma elasticum

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Credit: Dr. Ken Greer, VISUALS UNLIMITED /SCIENCE PHOTO LIBRARY

Caption: Pseudoxanthoma elasticum. Close-up of the skin of a patient with pseudoxanthoma elasticum (PXE). This disease, also known as Gronblad-Strandberg Syndrome, is an autosomal recessive genetic disorder of the connective tissue. Degeneration and calcification of elastic fibres causes premature ageing of the skin, including the yellow papules seen here. The disease progresses to affect the retina, gastrointestinal system and blood vessels,and can cause loss of central vision and internal haemorrhaging.

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Keywords: autosomal, caucasian, close up, close-up, condition, connective tissue, dermal, dermatological, dermatology, detail, disease, disorder, genetic disease, gronblad-strandberg syndrome, human body, medical, medicine, papules, people, person, premature ageing, pseudoxanthoma elasticum, pxe, recessive, skin, white, wrinkled

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