Credit: FRANCIS LEROY & MAYRIC HUART, BIOCOSMOS/SCIENCE PHOTO LIBRARY

Caption: Animation of a macrophage white blood cell infected with a Mycobacterium tuberculosis bacterium (red). Macrophages are cells of the body's immune system that phagocytose and destroy pathogens, dead cells and cellular debris. TB infection begins when the mycobacteria reach the pulmonary alveoli in the lungs, where they invade and replicate within the endosomes of alveolar macrophages. M. tuberculosis uses a number of strategies to avoid being killed by the macrophage. It inhibits the phagosome that it is encapsulated in from maturing. This prevents fusing with lysosomes, which contain enzymes that digest the bacteria.

Release details: Model release not required. Property release not required.

Keywords: animated, animation, bacterial, bacterium, black background, immune cell, immune system, infecting, infection, macrophage, maturation inhibition, mycobacterium tuberculosis, no-one, nobody, pathogen, pathogenic, phagocyte, tb, white blood cell

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Macrophage infected with TB bacterium

K004/3279 Rights Managed

Downloadable master

Duration: 00:00:20.21

Frame size: 1920x1080

Frame rate: 25

Audio: No

Format: QuickTime, Photo JPEG 100%, progressive scan, square pixels

File size: 172.0M

Original

Capture format: QuickTime Animation

Codec: H.264

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