Credit: FRANCIS LEROY & SEMPOT AMAURY, BIOCOSMOS/SCIENCE PHOTO LIBRARY

Caption: Urea cycle, animation. The urea cycle produces urea from ammonia, a toxic by-product of many biological processes. Urea is able to be safely excreted via the kidneys as urine. In the mitochondrial matrix of liver cells a carbamoyl group is transferred to ornithine by the enzyme ornithine transcarbamoylase to form citrulline. In the cell cytosol argininosuccinate synthetase catalyses the condensation of citrulline and aspartate to form argininosuccinate. This is then cleaved by argininosuccinase to arginine and fumarate. Arginine is hydrolysed to urea and ornithine by arginase and the cycle is able to start over.

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Keywords: ammonia, animated, animation, arginine, argininosuccinate, biochemical, biochemistry, biological, biology, black background, citrulline, cytosolic, excretion, excretory, label, labeled, labelled, labels, metabolic pathway, metabolism, mitochondrial, nitrogenous waste, no-one, nobody, ornithine cycle, text, urea, urea cycle

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Urea cycle, animation

K004/3293 Rights Managed

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Duration: 00:00:14.21

Frame size: 1920x1080

Frame rate: 30

Audio: No

Format: QuickTime, Photo JPEG 100%, progressive scan, square pixels

File size: 98.7M

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Capture format: QuickTime Animation

Codec: H.264

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