This colour enhanced coronal (frontal view) gross anatomic brain specimen demonstrates evidence of severe, endstage Alzheimer's disease with marked atrophy of the hippocampal formations (yellow and red) (which are very important for memory) with associated enlargement of the temporal horns of the lateral ventricles. There is also prominent generalized atrophy of the remaining portions of the temporal lobes (aqua) with enlargement of the sylvian fissures. There is also atrophy with enlargement of the third ventricle and bodies of the lateral ventricles.
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