Kinase molecule, secondary structure

Kinase molecule, secondary structure

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Credit: DR TIM EVANS/SCIENCE PHOTO LIBRARY

Caption: Kinase molecule, computer model. Kinases, also known as phosphotransferases, are enzymes that catalyse the transfer of phosphate groups from a high-energy phosphate-containing molecule (such as ATP or ADP) to a substrate (such as a protein, lipid or carbohydrate). This process is known as phosphorylation. The largest group of kinases are protein kinases. Up to 518 different types have been identified in humans and are used to transmit signals and control complex processes in cells. In this model the molecule's shape (secondary structure) is seen, comprising alpha helices (coils), beta sheets (arrows) and linking regions (lines).

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