Multiple myeloma of the spine. Coloured T2-weighted magnetic resonance imaging (MRI) scan of the spine of a 62-year-old male patient affected by multiple myeloma (Kahler's disease), showing osteolytic compression of the T11, L2 and L3 vertebrae. Multiple myeloma is a cancer of plasma cells, a type of white blood cell. In this condition, large numbers of abnormal plasma cells accumulate in the bone marrow, where they interfere with the production of normal blood cells. Bone lesions may develop, causing the bone to weaken and become vulnerable to fractures. Multiple myeloma is not curable, but can be treated with steroids, chemotherapy and stem cell transplants. Osteolysis is the resorption of bone by osteoclasts.
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