Helix-loop-helix DNA-binding domain

Helix-loop-helix DNA-binding domain

C023/8883 Rights Managed

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Credit: SCIENCE PHOTO LIBRARY

Caption: Helix-loop-helix DNA-binding domain. Illustration of a regulatory protein (blue) binding to DNA (deoxyribonucleic acid, orange helix) in a helix-turn-helix formation. Such protein-DNA binding can enhance or suppress expression of the genetic information carried by the DNA. In this type of DNA-binding protein, the short and long alpha-helices of the protein are joined by a 'loop' (centre left) and bound as a dimer to the DNA structure. The key protein component is called the 'recognition alpha helix'. For this artwork with labels, see C023/8882.

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