Zinc finger DNA-binding domain

Zinc finger DNA-binding domain

C023/8884 Rights Managed

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Caption: Zinc finger DNA-binding domain. Illustration of a regulatory protein (blue) binding to DNA (deoxyribonucleic acid, orange helix) in a zinc finger formation. Such protein-DNA binding can enhance or suppress expression of the genetic information carried by the DNA. In this type of DNA-binding protein, an alpha helix (cylinder) and two beta sheets (arrows) are co-ordinated around a zinc ion (yellow) to form a 'zinc finger' (upper left) that binds to the DNA. The key protein component is called the 'recognition alpha helix'. For this artwork without labels, see C023/8885.

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