Foot-and-mouth disease virus drug complex

Foot-and-mouth disease virus drug complex

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Credit: RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY

Caption: Foot-and-mouth disease virus drug complex. Computer artwork showing the structure of a molecule of the foot-and-mouth disease virus (FMDV) RNA-dependent RNA polymerase (RdRp), in complex with a template (pale pink) primer (mauve), RNA (ribonucleic acid) and the drug ribavirin (spheres, centre). Ribavirin is used to treat hepatitis C and viral haemorrhagic fevers by preventing viral RNA synthesis. It is a prodrug, which when metabolized resembles purine RNA nucleotides and contributes to virus extinction through lethal mutagenesis. RdRp is an enzyme that catalyses the replication of RNA from an RNA template.

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Keywords: antiviral, artwork, biochemical, biochemistry, biological, biology, biomolecule, catalyst, catalytic, complex, complexed, drug, enzyme, fmdv, foot and mouth disease, foot-and-mouth disease, genetic, genetics, illustration, interacting, interaction, microbiological, microbiology, molecular model, molecule, pharmaceutic, pharmaceutical, pharmacological, pharmacology, prevention, primer, prodrug, protein, proteomics, quaternary structure, rdrp, ribavirin, ribonucleic acid, rna, rna synthesis, rna-dependent rna polymerase, template, tertiary structure, transferase, treating, treatment, viral, virus, white background

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