Foot-and-mouth disease virus drug complex

Foot-and-mouth disease virus drug complex

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Credit: RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY

Caption: Foot-and-mouth disease virus drug complex. Computer artwork showing the structure of a molecule of the foot-and-mouth disease virus (FMDV) RNA-dependent RNA polymerase (RdRp), in complex with a template (pale pink) primer (mauve), RNA (ribonucleic acid) and the drug ribavirin (spheres, centre). Ribavirin is used to treat hepatitis C and viral haemorrhagic fevers by preventing viral RNA synthesis. It is a prodrug, which when metabolized resembles purine RNA nucleotides and contributes to virus extinction through lethal mutagenesis. RdRp is an enzyme that catalyses the replication of RNA from an RNA template.

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Keywords: alpha helix, antiviral, artwork, beta sheet, biochemical, biochemistry, biological, biology, biomolecule, catalyst, catalytic, complex, complexed, drug, enzyme, fmdv, foot and mouth disease, foot-and-mouth disease, genetic, genetics, helices, illustration, interacting, interaction, microbiological, microbiology, molecular model, molecule, pharmaceutic, pharmaceutical, pharmacological, pharmacology, prevention, primer, prodrug, protein, proteomics, rdrp, ribavirin, ribonucleic acid, rna, rna synthesis, rna-dependent rna polymerase, secondary structure, sheets, template, tertiary structure, transferase, treating, treatment, viral, virus, white background

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