SV40 antigen and tumor suppressor

SV40 antigen and tumor suppressor

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Credit: LAGUNA DESIGN/SCIENCE PHOTO LIBRARY

Caption: SV40 antigen and tumour suppressor. Molecular model of the simian virus (SV40) large T antigen bound to a retinoblastoma tumour suppressor (Rb). Large T antigens play a role in regulating the viral life cycle of the polyomaviridae viruses, such as SV40. SV40 is potentially tumour-causing in primates and humans. Rb proteins encourage normal cell cycles, thus preventing the formation of tumours. When the large T antigen binds to Rb, the tumour suppressor's action is blocked, and the development of malignant tumours becomes more likely.

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Keywords: artwork, biochemical, biochemistry, biological, biology, black background, complex, illustration, large t antigen, large tumour antigen, microbiological, microbiology, model, molecular, molecular model, molecular structure, molecule, no-one, nobody, polyomaviridae, protein, proteomics, rb, retinoblastoma, simian vacuolating virus 40, structure, sv40, tumour suppressor, viral, virology, virus

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