Caption: Myosin and actin interact in cross bridge power stroke cycling. Like skeletal and cardiac muscle tissue, smooth muscle cells do rely on crossbridge cycling between actin and myosin to develop force. However, in smooth muscle, crossbridge cycling cannot occur until myosin heads are activated as the end result of an activation cascade begun by a rise in cytosolic calcium levels.

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Keywords: actin, cross bridge cyclin, muscle, myosin, myosin heads, power stroke cycling, sarcomere

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Myosin and actin interact

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