Bone development, light micrograph

Bone development, light micrograph

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Caption: Timeline series of histologic sections of bone growth showing endochondral ossification. A: chondrocytes and cartilage matrix (blue), B: chondrocytes enlarging and dying, C: capillary invasion, and narrow new bone collar (pink), D: osteoblasts and bone marrow precursors occupy cartilage spaces and bone collar (pink) is forming, E: cartilage matrix provides surfaces for new bone deposits and bone collar (pink) well developed, F: cartilage now replaced with new bone matrix forming spongy bone and bone marrow.

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Keywords: biological, biology, bone, bone development, bone marrow, cartilage, chondrocyte, endochondral ossification, histological, histology, hyaline cartilage, light micrograph, light microscopy, section

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