Chloride channel and ivermectin complex

Chloride channel and ivermectin complex

C027/7780 Rights Managed

Request low-res file

530 pixels on longest edge, unwatermarked

Request/Download high-res file

Uncompressed file size: 50.3MB

Downloadable file size: 907.5KB

Price image Pricing

Please login to use the price calculator


Caption: Chloride channel and ivermectin complex. Computer model showing the structure of a glutamate-gated chloride channel from a parasitic nematode worm (Caenorhabditis elegans). This protein (red) is found in post-synaptic neuron membranes. Neurotransmitters bind to the upper portion and trigger a conformational change in the receptor that opens the chloride channel, dampening neuronal excitability. Ivermectin is an antiparasite drug. It is an allosteric agonist that opens chloride ion channels. It binds in the transmembrane domain of the receptor and stabilises the open-pore conformation.

Release details: Model release not required. Property release not required.

Keywords: 1, allosteric agonist, anti-parasite, anti-parasitic, antiparasitic, artwork, biochemical, biochemistry, bound, c elegans, c. elegans, caenorhabditis elegans, chemical, chemicals, chemistry, chloride ion channel, complex, complexed, cut-out, cut-outs, cutout, cutouts, drug, glutamate gated, glutamate-gated, illustration, ivermectin, medical, medicine, membrane, membrane-bound, membranes, model, molecular, molecule, molecules, nematode, nervous system, neural, neuron, neuronal, neurone, neurones, neurons, no-one, nobody, one, parasite, parasitic, parasitism, pharmacological, pharmacology, post-synaptic, protein, proteins, proteomics, receptor, single, structure, transmembrane, treatment, white background, worm

Licence fees: A licence fee will be charged for any media (low or high resolution) used in your project.