Protein Folding

Protein Folding

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Credit: KENNETH EWARD/BIOGRAFX/SCIENCE PHOTO LIBRARY

Caption: Newly-synthesized proteins in the cell, folding into their correct shapes in order to function properly. The enzyme UDP-glucose glycosyltransferase (UGGT) monitors folding in the endoplasmic reticulum (ER) of the cell. In this illustration, a UGGT enzyme (purple) checks new proteins (blue, upper left) for proper conformation, by examining specific indicator molecules (green, pink) attached to the proteins. Correctly-folded proteins are approved (right), while misfolded proteins (bottom) are degraded and their components are recycled.

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Keywords: biochemical, biochemistry, calnexin cycle, cell, cellular, chemical, chemistry, compound, compounds, endoplasmic, endoplasmic reticulum, enzyme, er, molecular model, molecular models, molecule, molecules, post-translational modification, protein, protein folding, protein synthesis, proteins, reticulum, udp-glucose glycosyltransferasem calnexin, uggt

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