Interleukin-12 protein molecule

Interleukin-12 protein molecule

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Credit: DR TIM EVANS/SCIENCE PHOTO LIBRARY

Caption: Interleukin-12 protein molecule. Molecular model of a molecule of the cytokine protein interleukin-12 (IL-12). The secondary structure of the molecule is seen here, containing alpha helices (spirals) and beta sheets (arrows). IL-12 is a cytokine (signalling compound) that is produced by dendritic cells and macrophages in the body when they encounter pathogens such as bacteria and viruses. IL-12 is involved in the development and function of T-cells. T-cells are white blood cells that are responsible for destroying pathogens. IL-12 also activates other cytokines, which go on to initiate other immune response molecules. This domino effect is known as a cascade.

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Keywords: 1, activation, alpha helices, arrows, beta sheet, biochemical, biochemistry, biological, biology, cascade, chemical, chemistry, corkscrew, cytokine, development, helical, helix, il-12, immune system, immunity, immunology, interleukin, interleukin-12, maturation, molecular, molecular model, molecule, one, protein, response, sheets, spirals, t-cells

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