RNA-binding protein, molecular model

RNA-binding protein, molecular model

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Credit: LAGUNA DESIGN/SCIENCE PHOTO LIBRARY

Caption: RNA-binding protein. Computer model of the RNA-binding protein ACF (APOBEC-1 complementation factor). It is thought that ACF functions as an RNA-binding subunit that docks APOBEC-1 with an RNA (ribonucleic acid) strand. APOBEC enzymes catalyse the breakdown (deamination) of the amino acid cytidine in nucleic acids (DNA - deoxyribonucleic acid, and RNA), changing it to uridine. Different APOBEC members use this process to achieve diverse human biological functions, such as inhibiting the replication of HIV. Studies suggest that ACF may also be involved in other RNA-editing or RNA-processing events.

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