Credit: RHYS LEWIS, AHS, DECD, UNISA/EQUINOX GRAPHICS/SCIENCE PHOTO LIBRARY

Caption: DNA missense point mutation. Animation showing a missense point mutation in the replication of DNA (deoxyribonucleic acid). As the DNA unravels, a helicase enzyme (red) is shown moving along the helix, separating the complementary strands. Labels appear showing the genetic code, the sequence of the nucleotide bases along a strand (cytosine, C, blue; guanine, G, yellow; adenine, A, green; thymine, T, red). A DNA polymerase enzyme is shown replicating a new strand and making a mistake (red area). The new complementary strands are formed, completing the replication process and the animation zooms in on the mistake (a mutation). Adjacent groups of three bases, known as codons, code for the production of amino acids (the basis of proteins). The codon affected here is ACC (for the amino acid threonine). This has mutated to ATC, which will produce a different amino acid (isoleucine). This is known as a missense mutation, as opposed to mutations that produce nonsense or no change (a silent mutation).

Release details: Model release not required. Property release not required.

Keywords: acc, adenine, amino acid, amino acids, animated, animation, artwork, atc, base, bases, biochemical, biochemistry, biological, biology, codon, codons, complementary strands, cytosine, deoxyribonucleic acid, dna, dna polymerase, enzyme, enzymes, genes, genetic, genetic code, genetics, graphic, guanine, helicase, illustration, isoleucine, missense, mistake, molecular, mutate, mutated, mutation, no-one, nobody, nucleotide, nucleotides, replicate, replicating, replication, strands, threonine, thymine

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DNA missense point mutation, animation

K005/6625 Rights Managed

Downloadable master

Duration: 00:00:40.04

Frame size: 1920x1080

Frame rate: 25

Audio: No

Format: QuickTime, Photo JPEG 100%, progressive scan, square pixels

File size: 1.0G

Original

Capture format: QuickTime Animation

Codec: PNG

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