Neutralizing human IgG1 B12 against HiV-1

Neutralizing human IgG1 B12 against HiV-1

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Credit: ALFRED PASIEKA/SCIENCE PHOTO LIBRARY

Caption: Crystal structure of a neutralizing human IgG1 B12 against HIV-1. Molecular model of the crystal structure of a neutralizing human IgG1 B12 against HIV-1. Antibody b12 recognizes the CD4-binding site of human immunodeficiency virus-1 (HIV-1) gp120 and is one of only two known antibodies against gp120 capable of broad and potent neutralization of primary HIV-1 isolates.

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