IgM rheumatoid factor with IgG1 FC

IgM rheumatoid factor with IgG1 FC

C029/8745 Rights Managed

Request low-res file

530 pixels on longest edge, unwatermarked

Request/Download high-res file

Uncompressed file size: 53.6MB

Downloadable file size: 1.4MB

Price image Pricing

Please login to use the price calculator


Caption: Structure of human IgM rheumatoid factor Fab in complex with its autoantigen IgG Fc. Molecular model of the structure of human IgM rheumatoid factor in complex with its autoantigen IgG Fc. Rheumatoid factors are the characteristic autoantibodies of rheumatoid arthritis, which bind to the Fc regions of IgG molecules. The structure implicates antigen-driven selection, following somatic mutation of germline genes, in the production of pathogenic rheumatoid factors.

Release details: Model release not required. Property release not required.

Keywords: antibodies, antigen, antigen-driven, arthritis, autoantibodies, autoantigen, bound, cgi, cut out, cut outs, cut-out, cut-outs, cutout, cutouts, digitally generated, fab, factor, factors, fc, genes, germline, human, igg, igm, model, molecular, molecules, mutation, pathogenic, rheuma, rheumatoid, selection, somatic, structure, white background

Licence fees: A licence fee will be charged for any media (low or high resolution) used in your project.