Credit: RHYS LEWIS, AHS, DECD, UNISA/EQUINOX GRAPHICS/SCIENCE PHOTO LIBRARY

Caption: DNA nonsense point mutation. Animation showing a strand of DNA (deoxyribonucleic acid) unravelling to display its genetic code, followed by an illustration of a nonsense point mutation. A helicase enzyme (red) is shown moving along the DNA molecule, separating the complementary strands. The genetic code is the sequence of the nucleotide bases along a strand (cytosine, C, blue; guanine, G, yellow; adenine, A, green; thymine, T, red). The sequence is labelled here, with adjacent groups of three bases known as codons, which code for the production of amino acids (the basis of proteins). The central codon here is GGA (for the amino acid glycine). This is shown mutating to TGA, which is a stop codon. This truncates the protein production, causing abnormal shortening. This is known as a nonsense mutation, as opposed to mutations that produce change (a missense mutation) or no change (a silent mutation).

Release details: Model release not required. Property release not required.

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DNA nonsense point mutation, animation

K005/8852 Rights Managed

Downloadable master

Duration: 00:00:43.16

Frame size: 1920x1080

Frame rate: 25

Audio: No

Format: QuickTime, Photo JPEG 100%, progressive scan, square pixels

File size: 1.5G

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Capture format: QuickTime Animation

Codec: PNG

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