Credit: RHYS LEWIS, AHS, DECD, UNISA/EQUINOX GRAPHICS/SCIENCE PHOTO LIBRARY

Caption: DNA nonsense point mutation. Animation showing a nonsense point mutation in the replication of DNA (deoxyribonucleic acid). As the DNA unravels, a helicase enzyme (red) is shown moving along the helix, separating the complementary strands. Labels appear showing the genetic code, the sequence of the nucleotide bases along a strand (cytosine, C, blue; guanine, G, yellow; adenine, A, green; thymine, T, red). A DNA polymerase enzyme is shown replicating a new strand and making a mistake (red area). The new complementary strands are formed, completing the replication process and the animation zooms in on the mistake (a mutation). Adjacent groups of three bases, known as codons, code for the production of amino acids (the basis of proteins). The codon affected here is GGA (for the amino acid glycine). This has mutated to TGA, which is a stop codon. This truncates the protein production, causing abnormal shortening. This is known as a nonsense mutation, as opposed to mutations that produce change (a missense mutation) or no change (a silent mutation).

Release details: Model release not required. Property release not required.

Keywords: adenine, amino acid, amino acids, animated, animation, artwork, base, bases, biochemical, biochemistry, biological, biology, codon, codons, complementary strands, cytosine, deoxyribonucleic acid, dna, dna polymerase, enzyme, enzymes, genes, genetic, genetic code, genetics, gga, glycine, graphic, guanine, helicase, illustration, missense, mistake, molecular, mutate, mutated, mutation, no-one, nobody, nucleotide, nucleotides, replicate, replicating, replication, stop codon, strands, thymine

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DNA nonsense point mutation, animation

K005/8853 Rights Managed

Downloadable master

Duration: 00:00:40.04

Frame size: 1920x1080

Frame rate: 25

Audio: No

Format: QuickTime, Photo JPEG 100%, progressive scan, square pixels

File size: 959.4M

Original

Capture format: QuickTime Animation

Codec: PNG

Please contact Science Photo Library if you require the original, or other formats.

 

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