T-cell receptor - MHC complex

T-cell receptor - MHC complex

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Caption: T-cell receptor - MHC complex. Computer model showing the molecular structure of a T-cell receptor (TCR, pink and blue) bound to an allogeneic (non-self) major histocompatibility complex (MHC) molecule (purple, grey and green). TCRs are found on the surface of T-cells, a type of white blood cell (lymphocyte). T-cells are part of the body's immune response. Engagement of the TCR with an antigen results in activation of its T-cell through a series of biochemical events, mediated by associated enzymes, co-receptors, and specialized accessory molecules. MHCs indicate whether a cell (or cells) is from the same organism as the T-cell. If they are non-self then an immune response is triggered and the T-cell receptors are configured to recognise the MHC.

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Keywords: 1, allogeneic, antigen, antigen recognition, artwork, biochemical, biochemistry, biological, biology, chemistry, heterodimer, illustration, immune response, immune system, immunity, lymphocyte, major histocompatibility complex, mhc, molecular model, molecule, non-self, one, pathogen, recognition, single, t-cell receptor, t-lymphocyte

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