Nucleus with nuclear pores in the nuclear membrane, coloured transmission electron micrograph (TEM). Ribosomes and polyribosomes in the periphery. The hepatocyte is a liver cell in the body that manufactures serum albumin, fibrinogen, and the prothrombin group of clotting factors. It is the main site for the synthesis of lipoproteins, ceruloplasmin, transferrin, complement, and glycoproteins. Hepatocytes manufacture their own structural proteins and intracellular enzymes. Synthesis of proteins is by the rough endoplasmic reticulum (RER), and both the rough and smooth endoplasmic reticulum (SER) are involved in secretion of the proteins formed. Magnification: x9,150 when shortest axis printed at 25 millimetres.
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