Purkinje neurons in cerebellum, LM Brightfield

Purkinje neurons in cerebellum, LM Brightfield


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Brightfield light micrograph of Purkinje neurons (nerve cells) in the human cerebellum. Purkinje nerve cells (black; Cajal Golgi stain) are flask-shaped cells with large dendrite extensions (processes). They are some of the largest neurons in the human brain. Purkinje cells are located between the molecular and granular layers of the cerebellum. Purkinje cells play a role in motor coordination. Nerve impulses travel to the Purkinje cells through their numerous dendrites. From here the impulse is passed on to the white matter deep in the cerebellar cortex. The cerebellum controls balance, posture and muscle coordination. It may also be involved in some cognitive functions such as attention, language, and in regulating fear and pleasure responses. Magnification: x40 when shortest axis printed at 25 millimetres.

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