Vitamin B1 crystals, LM

Vitamin B1 crystals, LM

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Credit: DENNIS KUNKEL MICROSCOPY/SCIENCE PHOTO LIBRARY

Caption: Light micrograph (LM) of Vitamin B1 (thiamine, thiamin) crystals. Vitamin B1 is present in blood plasma and cerebrospinal fluid and functions as thiamine coenzymes in the metabolism of carbohydrates and synthesis of NADPH and pentose sugars, deoxyribose and ribose. Systemic thiamine deficiency can lead to myriad problems including neurodegeneration, wasting, and death. Well-known syndromes caused by lack of thiamine are due to malnutrition or a diet high in thiamin-rich foods include Wernicke-Korsakoff syndrome and beriberi, diseases also common in chronic abusers of alcohol. Thiamine was first discovered by Umetaro Suzuki in Japan while researching how rice bran cured patients of beriberi. He named it aberic acid. Magnification: x40 when shortest axis printed at 25 millimetres.

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Keywords: 920407-22, aberic, acid, b, b-complex, b1, beriberi, blood, carbohydrate, cerebrospinal, coenzymes, colored, coloured, complex, crystal, crystals, deficiency, deoxyribose, false-colored, false-coloured, fluid, light, lm, malnutrition, metabolism, micrograph, nadph, neurodegeneration, pentose, plasma, ribose, sugars, syndrome, synthesis, thiamin, thiamine, vitamin, wasting, wernicke-korsakoff

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