Yellow fever vaccine production, 1940

Yellow fever vaccine production, 1940

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Credit: Rocky Mountain Laboratories, National Institutes of Health/SCIENCE PHOTO LIBRARY

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Caption: Yellow fever vaccine production. Researchers in the 1940s passing chicken embryo pulp through centrifuge tubes as part of the production of a vaccine for yellow fever. Research by Hargett and Burruss facilitated the production of this vaccine without the use of human serum. A cell culture method was used to produce the vaccine. Yellow fever is a tropical viral infection transmitted by mosquito bite. It causes fever, nausea, and headaches. A toxic form of the disease can lead to jaundice, internal bleeding, and death. An effective vaccine was developed in the late 1930s. Photographed in 1940 at the Yellow Fever Unit in the Rocky Mountain Laboratory, Hamilton, Montana, USA.

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