Anandamide and cannabinoid receptor, molecular model

Anandamide and cannabinoid receptor, molecular model

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Credit: RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY

Caption: Anandamide and cannabinoid receptor. Computer-generated molecular model of anandamide molecule (red, white and blue) with a cannabinoid type 1 (CB1) receptor complex (multicoloured), to which it binds. CB1 is a cell membrane receptor found mainly in the nervous system. Anandamide is a natural cannabinoid neurotransmitter produced by the body. The binding of anandamide to the receptor induces cellular responses inside the cell. Anandamide plays a role in memory, regulating feeding behaviour and motivation. CB1 receptors also bind tetrahydrocannabinol (THC), the principle psychoactive compound in the drug cannabis.

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