Neuroblastoma cells, fluorescence light micrograph

Neuroblastoma cells, fluorescence light micrograph

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Caption: Neuroblastoma cells. Fluorescence light micrograph of cells from a type of brain cancer (neuroblastoma) in a human patient. The cells are stained for cell nuclei (DNA, red) and cellular cytoskeleton (green). Cancer cells spread in the body with the help of mutated genes that drive changes in the cytoskeleton of the cells, the protein filaments and microtubules that control cell shape and contribute to cell movement. Study of the mechanisms by which cancer cells move through the body may lead to targeted therapies that reverse these processes. Neuroblastoma is a common cancer in very young children. It arises from cells in the sympathetic nervous system. The stains used here were primary antibodies for actin and tubulin detection, and propidium iodine for DNA staining.

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