Dysplasia in skin, light micrograph

Dysplasia in skin, light micrograph

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Credit: BIOPHOTO ASSOCIATES/SCIENCE PHOTO LIBRARY

Caption: Dysplasia in skin. Light micrograph of tissue from human skin in a case of dysplasia. Here, the normal sequence of skin cell formation and shedding has been disrupted. This can be a precursor to cancer. Across top are layers of stratified squamous epithelium, but unlike in normal skin, darkly-stained cells from the basal layer (across centre) have moved far up towards the surface of the skin. Normally, the cell nuclei would be smaller than the skin cells as the cytoplasm expanded, but this hasn't happened here. For normal skin epithelium, see (see C001/8842).

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