Pesticide & cell

Pesticide & cell

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Credit: JACOPIN / BSIP/SCIENCE PHOTO LIBRARY

Caption: Illustration of the action of pesticides on human cells, increasing the risk of non-Hodgkin's lymphoma, Parkinson's disease and prostate cancer. The first action of pesticides on B-lymphocytes is genotoxic, pesticides reach cellular DNA and cause the displacement of the Bcl2 gene (yellow) of chromosome 18 towards chromosome 14, causing an anarchic proliferation of B-lymphocytes. The second action affects NK-lymphocytes, which are specialized in eliminating abnormal cells such as mutated B-lymphocytes. Pesticides disrupt the production of molecules that usually allow abnormal cells to be eliminated; mutated B-lymphocytes proliferate anarchically as they are no longer eliminated by NK-lymphocytes.

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Keywords: agriculture, artwork, b lymphocyte, cell, cell division, chemical product, cytology, fungicide, genetic mutation, genetics, human, immunology, insecticide, leucocyte, leukocyte, lymphocyte, medicine, mutation, nk lymphocyte, pesticide, pollution, toxic product, tumour suppressor, weed-killer

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