Alpha1-antitrypsin molecule

Alpha1-antitrypsin molecule

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Credit: LAGUNA DESIGN/SCIENCE PHOTO LIBRARY

Caption: Alpha1-antitrypsin molecule. Computer model showing the structure of alpha1-antitrypsin (blue-green) with its reactive loop (pink). This protein, also known as alpha-1 proteinase inhibitor, is a type of serine protease inhibitor (serpin) and is named after its ability to covalently bind and irreversibly inactivate serine proteases, including the digestive enzyme trypsin. It plays a key role in mediating inflammation and a deficiency results in the lung disease emphysema.

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