Januvia diabetes drug molecule

Januvia diabetes drug molecule

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Credit: DR MARK J. WINTER/SCIENCE PHOTO LIBRARY

Caption: Januvia diabetes drug, molecular model. Januvia (sitagliptin) is a hypoglycaemic drug, one that reduces blood sugar levels. Diabetes is a condition in which blood sugar levels can get dangerously high due to a lack of insulin, the hormone that reduces them. Januvia works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP- 4). DPP-4 rapidly deactivates the incretin hormone GLP-1 (glucagon-like peptide 1), which promotes insulin release. Hence, inhibiting DPP-4 prolongs the effects of GLP-1, keeping insulin levels high. Atoms are colour-coded: carbon (grey), hydrogen (yellow), oxygen (red), nitrogen (blue) and fluorine (green). Januvia is marketed by Merck, and was approved in the USA in October 2006.

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Keywords: anti-diabetic, anti-hyperglycaemic, ball and stick, biochemical, biochemistry, biological, biology, blood sugar, chemical, chemistry, compound, compounds, diabetes, diabetic, dipeptidyl peptidase-4, dpp-4 inhibitor, drug, enzyme inhibitor, glp-1, glucagon-like peptide 1, glucose, high blood sugar, hyperglycaemia, hypoglycaemic, incretin, inhibition, inhibitor, januvia, medical, medication, medicine, merck, molecular, molecular model, molecule, one, oral, pharmaceutical, pharmaceutics, pharmacological, pharmacology, single, sitagliptin

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