Girl with growth disorder

Girl with growth disorder

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Caption: Girl with growth disorder. Young girl (centre) with dyschondrosteosis, seen with her two sisters. She is 11-years-old, yet is barely taller than her 4-year-old sister (left), and much shorter than her 13-year-old sister (right). Dystchondrosteosis is a rare genetic condition, caused by mutations in the SHOX gene found on the X and Y chromosomes. It is characterised by mesomelic dwarfism (shortened forearms and legs) and bowing of the bones. Treatment is by injection of growth hormone such as genotropin, which ceases at puberty. Dyschondrosteosis is also known as Leri-Weill syndrome.

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