Creatinine crystals, light micrograph

Creatinine crystals, light micrograph

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Credit: ANTONIO ROMERO/SCIENCE PHOTO LIBRARY

Caption: Polarized light micrograph of creatinine crystals, a breakdown product of creatine phosphate, a molecule of major importance for energy production in muscle tissue. Creatinine is removed or cleared from the blood plasma mainly by glomerular filtration, and is excreted in the urine. Creatinine levels in blood and urine may be used to calculate the creatinine clearance rate, which correlates with the glomerular filtration rate, and is therefore an indicator of kidney function. If renal filtration is deficient, creatinine blood levels rise. A low or decreased creatinine clearance level may indicate such conditions as glomerulonephritis, ureteral obstruction, or pyelonephritis (kidney infection), and may be associated with an increased risk for the development of diabetes mellitus type 2 and prostate cancer. Field of view size: 0. 74 x 1. 11 mm.

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Keywords: bacteremia, biochemical, biochemistry, chemistry, chronic renal failure, creatine, creatinine, creatinine clearance, creatinine level, crystal, diagnosis, excretion, glomerular filtration, glomerular filtration rate, glomeruli, glomerulonephritis, haematological, haematology, health, hematology, kidney, kidney disease, kidney function, light micrograph, medical, medicine, metabolic pathways, metabolism, metabolite, metabolomics, molecular biology, muscle metabolism, nephrology, nephron, nephropathy, pathological, pathology, photomicrograph, physiological, physiology, polarized light, prostate cancer, pyelonephritis, renal disease, renal dysfunction, renal function, renal physiology, serum creatinine, ureteral obstruction, urinalysis, urine

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