Methotrexate drug

Methotrexate drug

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Credit: DR P. MARAZZI/SCIENCE PHOTO LIBRARY

Caption: Methotrexate drug. Syringe containing the antifolate drug methotrexate. It works by inhibiting the metabolism of folic acid (vitamin B9), which is necessary for the production and maintenance of new cells. Methotrexate is used to treat cancers, and also some autoimmune diseases such as myositis (muscle inflammation), Crohn's disease (intestinal inflammation), psoriasis (skin inflammation), rheumatoid arthritis (joint inflammation), and scleroderma (connective tissue hardening).

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