Adenovirus. Molecular model showing the external protein structure of an adenovirus 5 (Ad5) particle. Adenoviruses are the largest viruses not to have a protein coat covering their capsid. The capsid is icosahedral, having 20 triangular faces made up of regular arrangements of hexon capsomeres (red). Penton capsomeres (yellow) make up the 12 vertices, with a fibre and knob structure (not seen) protruding from each. Cement proteins are cyan. Inside the capsid is the genetic material (DNA, not shown). Adenoviruses commonly cause infections of the upper respiratory tract and eyes. Adenoviruses are popular vectors for gene therapy.
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