Okazaki fragments experiments, 1960s

Okazaki fragments experiments, 1960s

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Credit: RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY

Caption: Okazaki fragments experiments, 1960s, illustration. Okazaki fragments are short, discontinuous segments of single-stranded DNA (deoxyribonucleic acid), synthesized during DNA replication. They were discovered in a series of experiments carried out in the 1960s at Nagoya University by a Japanese research team that included molecular biologists Reiji Okazaki (1930-1975), Tsuneko Okazaki (born 1933) and Kiwako Sakabe. These three figures are shown at lower left, including the husband-wife team of the Okazakis. The research was carried out on the bacterium Escherichia coli.

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