Nemonapride in complex with dopamine receptor, illustration

Nemonapride in complex with dopamine receptor, illustration

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Credit: RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY

Caption: Nemonapride in complex with dopamine receptor. Computer illustration showing the structure of a molecule of the antipsychotic drug nemonapride (spheres) bound to a dopamine receptor (ribbons) in a cell membrane (rods, horizontal) in the central nervous system (CNS). Dopamine receptors are implicated in the pathogenesis and treatment of nearly every neuropsychiatric disorder. Thousands of drugs interact with these receptors. Nemonapride is used to treat schizophrenia by acting as a D2 and D3 dopamine receptor antagonist.

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