GDNF complexed with GDF15, molecular model

GDNF complexed with GDF15, molecular model

C038/5794

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Caption

GDNF complexed with GDF15. Computer illustration showing a glial cell line-derived neurotrophic factor (GDNF) molecule (red) bound to a growth and differentiation factor 15 (GDF15) molecule (fuchsia) in a cell membrane (white) of the brainstem. GDF15 regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GDF15 levels increase in response to tissue stress and injury, and elevated levels are associated with body weight loss in numerous chronic human diseases.

Release details

Model release not required. Property release not required.

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